McAlester News-Capital, McAlester, OK

Features

March 6, 2013

Can eyes see outside of the head?

PITTSBURGH — Recently, we have witnessed remarkable, fictional-sounding advancements in science and medicine. There's a guy who can hear color, another with a bionic eye attached to his brain, and a woman fighting back against the debilitating symptoms of multiple sclerosis by placing electrodes on her tongue. But for our next trick, we're going to need a bucket of tadpoles with eyes on their butts and some good old-fashioned alternating current. In other words, things are about to get all kinds of weird.

There's a great deal of wow to unpack here, so let's take it piece by piece. Using embryos from the African clawed frog (Xenopus), scientists at Tufts' Center for Regenerative and Developmental Biology were able to transplant eye primordia — basically, the little nubs of flesh that will eventually grow into an eye — from one tadpole's head to another's posterior, flank or tail. They don't play around with nerve endings or "wiring" or anything like that. They just cut out the cells from the head, slice open a bit of the tail, and jam them in.

As the eyes grow, they send out snaking tendrils of nerve fiber, or axons. We know this because the "tissue donor" tadpoles — a term that makes it sound like they had a choice — were injected with tdTomato, a fluorescent red protein. This allowed the researchers to watch innervation, or nerve growth, as it happened. Of those eye primordia that sent out feelers, nearly half hardwired directly into the spine, while the other half built connections to the nearby stomach. None of the tadpoles grew tdTomato-marked pathways to the brain.

Before they could test the ectopic eyes however, the native ones had to be severed and removed. Otherwise, how would the scientists know which of the tadpole's three eyes was truly seeing? (Note: Severing optical nerves sounds like nasty business, but even these partially-developed tadpoles received anesthesia via fish sedative. Wounds healed completely within 24 hours.)

Text Only | Photo Reprints
Features
  • Fairly Snotty McAlester livestock report

    On Tuesday, 1,200 head of cattle were sold at the McAlester Union Stockyards. Steers sold $2 to $9 higher than at the last sale and heifers sold $4 to $8 higher.

    April 18, 2014 1 Photo

  • Low blood-sugar levels make for grousing spouses

    Husbands and wives reported being most unhappy with their spouses when their blood-sugar levels were lowest, usually at night, according to research released this week in the Proceedings of the National Academy of Sciences. Missing a meal, dieting or just being hungry may be the reason, researchers said.

    April 18, 2014

  • treadmill-very-fast.jpg Tax deduction for a gym membership?

    April marks another tax season when millions of Americans will deduct expenses related to home ownership, children and education from their annual tax bill. These deductions exist because of their perceived value to society; they encourage behaviors that keep the wheels of the economy turning. So why shouldn't the tax code be revised to reward preventive health?

    April 17, 2014 1 Photo

  • David Cantrell OSU Extension: Cattle tips for spring

    As we continue to move into spring here in Pittsburg County and cattle prices are at an all-time high, here are a few basic management tips to ensure herd health and productivity of the herd.

    April 16, 2014 1 Photo

  • RICHARDSON 50 1.jpg Richardsons celebrate 50 years of marriage

    Haileyville High School graduates Jim and Connie Richardson, of rural Claremore, will celebrate their 50th wedding anniversary Saturday.

    April 15, 2014 2 Photos

  • MHS Student Painters MHS Student Paintings

    April 14, 2014 1 Photo

  • Pet of the Week Pet of the Week

    April 11, 2014 1 Photo

  • Book Sale Book Sale

    April 10, 2014 1 Photo

  • Miss Teen McAlester Miss Teen McAlester

    April 9, 2014 1 Photo

  • 1 Week of the Young Child Photos

    April 9, 2014 9 Photos

Seasonal Content
AP Video
Raw: Orthodox Christians Observe Easter Rite Ceremony Marks 19th Anniversary of OKC Bombing Raw: Four French Journalists Freed From Syria Raw: Massive 7.2 Earthquake Rocks Mexico Captain of Sunken SKorean Ferry Arrested Raw: Fire Destroys 3 N.J. Beachfront Homes Raw: Pope Presides Over Good Friday Mass Raw: Space X Launches to Space Station Superheroes Descend on Capitol Mall Man Charged in Kansas City Highway Shootings Obama Awards Navy Football Trophy Anti-semitic Leaflets Posted in Eastern Ukraine Raw: Magnitude-7.2 Earthquake Shakes Mexico City Ceremony at MIT Remembers One of Boston's Finest Raw: Students Hurt in Colo. School Bus Crash Raw: Church Tries for Record With Chalk Jesus Raw: Faithful Celebrate Good Friday Worldwide Deadly Avalanche Sweeps Slopes of Mount Everest Police Arrest Suspect in Highway Shootings Drought Concerns May Hurt Lake Tourism
NDN Video
Jabari Parker's Top 5 Plays From Duke Career Kourtney Kardashian Is a Bikini Babe More Manpower Than Ever Expected At 4/20 Rally Debunk'd: Miley Cyrus AIDS, Cheeseburgers Cause Cancer, Military Warning Bill Previewing the NBA playoffs Raw: Orthodox Christians Observe Easter Rite My name is Cocaine Raw: Space X Launches to Space Station Lohan Gets Candid About Her Sex List The 2014 New York Auto Show Meet Johnny Manziel's New Girlfriend Chelsea Clinton Announces Pregnancy Funny: Celebrating Easter with Martha Stewart and Friends Man Accuses 'X-Men' Director Bryan Singer of Sexually Abusing Him As a Teenager Man hit with $525 federal fine after he doesn't pay for soda refill Lea Michele & Naya Rivera Feuding? Jabari Parker declares for the NBA draft Singing Nun Belts Out Cyndi Lauper New West, Texas Explosion Video Swim Daily, Throwback Thursday
Parade
Magazine

Click HERE to read all your Parade favorites including Hollywood Wire, Celebrity interviews and photo galleries, Food recipes and cooking tips, Games and lots more.